Biostimulators are groundbreaking preparations used in aesthetic medicine, whose main task is to stimulate the skin's natural regenerative processes.
Treatment with biostimulators allows for long-lasting rejuvenation, improved firmness, elasticity, and density of the skin, without the effect of artificial filling. Biostimulators work mainly by stimulating fibroblasts to produce collagen and elastin, which leads to the restoration of the structure of the skin and subcutaneous tissue.
Unlike classic fillers, such as hyaluronic acid, tissue biostimulators do not work by mechanically filling wrinkles, but activate the natural processes responsible for collagen production, making the effects of biostimulation more subtle and long-lasting.
Biostimulators are excellent at reducing wrinkles and furrows by stimulating fibroblasts to produce collagen, which leads to natural filling and smoothing of the skin.
By stimulating collagen and elastin production, biostimulation helps restore skin firmness and elasticity, improving its tone and structure.
Preparations containing polynucleotides, calcium hydroxyapatite, or amino acids stimulate the reconstruction and thickening of skin and subcutaneous tissue structures, which eliminates the effect of sagging skin.
Treatments using tissue biostimulators are used to restore facial volume in a natural way, emphasizing facial features and providing a lifting effect.
Biostimulators improve the overall quality of the skin—they increase its hydration, smoothness, and radiance.
By supporting the skin's natural regenerative processes, biostimulation aids skin regeneration after treatments or excessive sun exposure.
Although biostimulants used in aesthetic medicine are safe, there are certain contraindications:
The procedure using tissue biostimulators is minimally invasive and does not require a long recovery period. It is most often performed under local anesthesia.
Course of treatment:
The entire procedure consists of several treatments in a series, depending on the dosage and frequency of application, with intervals of several weeks to several months. The effects of the treatment are visible gradually, as collagen production is stimulated.
At Dr. Jagielska's clinic, biostimulation treatments are performed by Dr. Aleksandra Jagielska, a specialist with over 20 years of experience in aesthetic and regenerative medicine.
Doctor Aleksandra Jagielska graduated from the Medical Academy in Warsaw and specialized in dermatology and venereology. She is a member of prestigious international scientific organizations, and her particular area of interest is modern methods of skin stimulation—tissue biostimulators, collagen stimulators, hyaluronic acid, and regenerative treatments.
Her holistic approach to patients and individually tailored treatment protocols guarantee the safety and high effectiveness of the therapy. For more information about Dr. Jagielska, please visit the clinic's website: specialists - Dr. Aleksandra Jagielska.
1. T. A. Rochetti Bezerra et al., “Recent Advances in Collagen Biostimulators for Facial Rejuvenation: A Systematic Review in Aesthetic Dermatology,” 2025.
2.C. H. Naka et al., “Collagen bio-stimulators in facial rejuvenation: A literature review,” RSD Journal, 2024